Taxol
Catalog No. ABIN1027819
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Quick Overview for Taxol (ABIN1027819)
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Purpose
- Microtubule stabilizer
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Characteristics
- Microtubule stabilizing agent.
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Purity
- >98 % (TLC), NMR (Conforms)
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Chemical Name
- (2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate, Paclitaxel
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Formula
- C47H51NO14
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Solubility
- Soluble in DMSO, ethanol or acetonitrile
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Comment
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Source: Synthetic.
Appearance: White solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility R68- Possible risk of irreversible effects Hazard Phrases: H318-H361f-H341-H332-H312-H302-H335-H315-H334-H317 Precautionary Phrases: P280-P305+P351+P338-P260-P261-P342+P311
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Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility R68- Possible risk of irreversible effects Hazard Phrases: H318-H361f-H341-H332-H312-H302-H335-H315-H334-H317 Precautionary Phrases: P280-P305+P351+P338-P260-P261-P342+P311
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Storage
- -20 °C
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Background
- Paclitaxel is a mitotic inhibitor that promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis.
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Molecular Weight
- 853.9
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CAS-No
- 33069-62-4
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