Docetaxel
Catalog No. ABIN1027821
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Quick Overview for Docetaxel (ABIN1027821)
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Purpose
- Microtubule stabilizer
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Characteristics
- Microtubule stabilizing agent.
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Purity
- >98 %
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Chemical Name
- (2α,5β,7β,10β,13α)-4-Acetoxy-1,7,10-trihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
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Formula
- C43H53NO14
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Solubility
- Soluble to 100 mM in DMSO, and to 100 mM in ethanol
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Comment
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Source: Synthetic.
Appearance: White solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Handling Advice
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Storage
- -20 °C
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Background
- Docetaxel is a semi-synthetic analogue of paclitaxel differing at two positions in its chemical structure. It also binds and stabilizes microtubules which leads to cell cycle arrest and apoptosis.
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Molecular Weight
- 807.88
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CAS-No
- 114977-28-5
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