Deguelin
Catalog No. ABIN1027843
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Quick Overview for Deguelin (ABIN1027843)
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Purpose
- Akt inhibitor
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Characteristics
- Akt inhibitor.
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Purity
- >98 %
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Chemical Name
- (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
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Formula
- C23H22O6
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Solubility
- Soluble to 50 mM in ethanol and to 100 mM in DMSO
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Comment
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Source: Synthetic.
Appearance: Cream Solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Storage
- -20 °C
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Background
- Deguelin is a rotenoid, and a naturally occurring insecticide. Deguelin displays anti-cancer activity by inhibiting the growth of pre-cancerous and cancerous cells. High doses may have negative effects on the heart, lungs and nerves however. Deguelin has also been shown to have a correlation with Parkinson’s disease in rats.
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Molecular Weight
- 394.42
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CAS-No
- 522-17-8
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