Sulindac Sulfone
Catalog No. ABIN1027865
$261.60
Plus shipping costs $50.00
Shipping to:
United States
Delivery in 3 to 5 Business Days
Quick Overview for Sulindac Sulfone (ABIN1027865)
-
-
Purpose
- Sulindac metabolite
-
Characteristics
- Modulates beta-catenin-mediated effects.
-
Purity
- >98 %
-
Chemical Name
- {(1Z)-5-Fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl}acetic acid
-
Formula
- C20H17FO4S
-
Solubility
- Soluble to 25 mM in DMSO, 3 mM in ethanol
-
-
-
-
Comment
-
Source: Synthetic.
Appearance: Yellow solid -
Restrictions
- For Research Use only
-
-
-
Format
- Solid
-
Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
-
Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
-
Storage
- -20 °C
-
-
-
Background
- Sulindac is a nonsteroidal anti-inflammatory drug that is known to prevent recurrence and reduce colorectal polyps. It is a prodrug that is metabolized to a sulfide and sulfone derivative in vivo. The mechanism of action of both is the selective induction of apoptosis. The anti-inflammatory properties of sulindac are mediated by COX inhibition.
-
Molecular Weight
- 372.41
-
CAS-No
- 59864-04-9
-
-
You are here:
