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The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
, peroxisome proliferator-activated receptor gamma coactivator 1-beta-like
, ERR ligand 1
, PPAR gamma coactivator-1beta protein
, PPAR-gamma coactivator 1-beta
, peroxisome proliferator-activated receptor gamma coactivator 1 beta
, peroxisome proliferator-activated receptor gamma coactivator 1-beta
, peroxisome proliferative activated receptor, gamma, coactivator 1 beta
, peroxisome proliferator-activated receptor gamma coactivator 1beta-2a
, PGC-1-related estrogen receptor alpha coactivator