Progesterone Receptor antibody (AA 919-933)

Catalog No. ABIN1042663

This Mouse Monoclonal antibody specifically detects Progesterone Receptor in WB and IP. It exhibits reactivity toward Human, Rat, Mouse and Rabbitand has been mentioned in 1 publication.

Quick Overview for Progesterone Receptor antibody (AA 919-933) (ABIN1042663)

Target: Progesterone Receptor (PGR)

Reactivity: Human, Rat, Mouse, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: C262

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 919-933

Sequence: ILAGMVKPLL FHKK

Specificity: Human PR-A and PR-B isoforms. Cross reacts with mouse, rat and rabbit PR

Purification: Protein G

Immunogen: Synthetic peptide to C-terminal tail of human progesterone receptor (PR). (aa 919-933 ILAGMVKPLLFHKK)

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline use at 5-10 μg/mL

Comment:

Myeloma, fusion partners: FoxNY ( mouse myeloma from Balb/c origin)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody containing PBS + 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-Progesterone Receptor antibody (ABIN1042663)

Weigel, Beck, Estes, Prendergast, Altmann, Christensen, Edwards: "Ligands induce conformational changes in the carboxyl-terminus of progesterone receptors which are detected by a site-directed antipeptide monoclonal antibody." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 10, pp. 1585-97, (1992) (PubMed).

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: Progesterone Receptor 

Background: Synonyms:
NR3C3 antibody,Nuclear receptor subfamily 3 group C member 3 antibody,PGRantibody,PR antibody,PRA antibody,PRB antibody,PRGR_HUMAN antibody,Progesterone receptorantibody,Progestin receptor form A antibody,Progestin receptor form B antibody

OMIM: 607311

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration