RTN4RL2 antibody (C-Term)

Catalog No. ABIN1077412

Product Details anti-RTN4RL2 Antibody

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTN4RL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal RTN4RL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RTN4RL2.

Isotype: IgG

Application Details

Application Notes: RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 μg/mL.

Comment:

(CT) Reticulon 4 receptor-like 2 protein

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: RTN4RL2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for RTN4RL2

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Alternative Name: RTN4RL2 (RTN4RL2 Products)

Background: Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Synonyms: Reticulon 4 receptor-like 2, NgR2, NGRH1, NGRL3, Nogo receptor-like 3, Nogo-66 receptor homolog 1, Nogo-66 receptor-related protein

Molecular Weight: 46 kDa (calculated)

Gene ID: 349667

NCBI Accession: NP_848665