RTN4RL2 antibody (AA 241-337)

Catalog No. ABIN749483

There are 2+ publications for this product available. The Rabbit Polyclonal anti-RTN4RL2 antibody is suitable to detect RTN4RL2 in samples from Human. It has been validated for WB, IF, IHC (p) and IHC (fro).

Quick Overview for RTN4RL2 antibody (AA 241-337) (ABIN749483)

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTN4RL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RTN4RL2 Antibody

Binding Specificity: AA 241-337

Purpose: IFNGR2 Polyclonal Antibody

Cross-Reactivity: Cow, Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNGR2

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-RTN4RL2 antibody (ABIN749483)

Xia, Gao, Zhang, Wang, Zhao, Che, Ao, Yang, Wang, Lei: "Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells." in: Cell death discovery, Vol. 2, pp. 15065, (2016) (PubMed).

Kunis, Baruch, Rosenzweig, Kertser, Miller, Berkutzki, Schwartz: "IFN-?-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair." in: Brain : a journal of neurology, Vol. 136, Issue Pt 11, pp. 3427-40, (2013) (PubMed).

Target Details for RTN4RL2

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Alternative Name: NGR2

Background:

Synonyms: AF-1, IFGR2, IMD28, IFNGT1, Interferon gamma receptor 2, IFN-gamma receptor 2, IFN-gamma-R2, Interferon gamma receptor accessory factor 1, Interferon gamma transducer 1, IFNGR2

Background: Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2.

Gene ID: 3460

UniProt: P38484