CCL17 antibody (C-Term)

Catalog No. ABIN1077445

This Rabbit Monoclonal antibody specifically detects CCL17 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CCL17 antibody (C-Term) (ABIN1077445)

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CCL17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL17 Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal CCL17 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CCL17.

Isotype: IgG

Application Details

Application Notes: CCL17 antibody can be used for detection of CCL17 by Western blot at 1 - 2 μg/mL.

Comment:

(CT) Chemokine (C-C motif) ligand 17

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Target Details for CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: CCL17

Background: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.
Synonyms: Chemokine (C-C motif) ligand 17, small inducible cytokine subfamily A (Cys-Cys) member 17, SCYA17, thymus and activation-regulated chemokine, TARC, ABCD-2, A-152E5.3

Molecular Weight: 10 kDa

Gene ID: 6361

NCBI Accession: NP_002978