Cellular Fibronectin antibody
Reactivity: Human, Chicken, Guinea Pig, Rabbit, Rat
IHC, WB, ELISA
Host: Mouse
Monoclonal
DH1
unconjugated
1 image
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- Target See all Cellular Fibronectin products
- Cellular Fibronectin (Fibronectin, Cellular)
- Reactivity
- Human, Chicken, Guinea Pig, Rabbit, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cellular Fibronectin antibody is un-conjugated
- Application
- Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- Specificity
- The antibody is specific to extradomain A (EDA) sequence of a cellular fibronectin and recognizes thus only the cellular fibronectin. Mab DHI has been shown to specifically block chondrocyte condensation in chicken embryos (5). The antibody crossreacts with human, chicken, rat, rabbit and guinea pig
- Immunogen
- Monoclonal antibody (Mab) to cFn is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Purified fibronectin from A8387 fibrosarcoma cells was used as an immunogen (21).
- Clone
- DH1
- Isotype
- IgG1
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- Application Notes
- No reactivity with paraffin sections. Working dilution in western blotting is at least 1:1000.
- Restrictions
- For Research Use only
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- Storage
- 4 °C
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- Target
- Cellular Fibronectin (Fibronectin, Cellular)
- Alternative Name
- Cellular Fibronectin (cFn) (Cellular Fibronectin Products)
- Synonyms
- FN antibody, cig antibody, fibronectin antibody, finc antibody, lets antibody, msf antibody, fibronectin 1 antibody, fn1 antibody
- Background
- The monoclonal antibody DH1 recognizes only cellular form of Fibronectin. DH1 is specific to the extra domain A (EDA) of the molecule. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas.
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