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THO Complex 4 antibody

THOC4 Reactivity: Human, Mouse, Xenopus laevis WB, ELISA, IF, IP, IHC (p), ICC, ChIP, EM, FACS Host: Mouse Monoclonal 11G5 unconjugated
Catalog No. ABIN108543
  • Target See all THO Complex 4 (THOC4) Antibodies
    THO Complex 4 (THOC4)
    Reactivity
    • 45
    • 16
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Xenopus laevis
    Host
    • 43
    • 2
    Mouse
    Clonality
    • 41
    • 4
    Monoclonal
    Conjugate
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This THO Complex 4 antibody is un-conjugated
    Application
    • 32
    • 23
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), Electron Microscopy (EM), Flow Cytometry (FACS)
    Purification
    Protein A
    Immunogen
    Recombinant human ALY / REF fusion protein
    Clone
    11G5
    Isotype
    IgG1
    Top Product
    Discover our top product THOC4 Primary Antibody
  • Application Notes
    Optimal antibody dilution should be determined by titration, however as a guideline try: IHC-P: Use a concentration of 1 μg/mL. ICC/IF: 1/50. PubMed: 17103222 WB: 1/1500. Detects a band of approximately 32 kDa (predicted molecular weight: 27 kDa).
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Ding, Enriquez-Algeciras, Dave, Perez-Pinzon, Bhattacharya: "The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis." in: EMBO reports, Vol. 13, Issue 3, pp. 230-6, (2012) (PubMed).

    Domínguez-Sánchez, Sáez, Japón, Aguilera, Luna: "Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers." in: BMC cancer, Vol. 11, pp. 77, (2011) (PubMed).

    Thomas, Lischka, Müller, Stamminger: "The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity." in: PLoS ONE, Vol. 6, Issue 7, pp. e22671, (2011) (PubMed).

    Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, (2010) (PubMed).

    Katahira, Inoue, Hurt, Yoneda: "Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA." in: The EMBO journal, Vol. 28, Issue 5, pp. 556-67, (2009) (PubMed).

    Nojima, Hirose, Kimura, Hagiwara: "The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15645-51, (2007) (PubMed).

    van Koningsbruggen, Straasheijm, Sterrenburg, de Graaf, Dauwerse, Frants, van der Maarel: "FRG1P-mediated aggregation of proteins involved in pre-mRNA processing." in: Chromosoma, Vol. 116, Issue 1, pp. 53-64, (2007) (PubMed).

    Kim, Yong, Kataoka, Abel, Diem, Dreyfuss: "The Y14 protein communicates to the cytoplasm the position of exon-exon junctions." in: The EMBO journal, Vol. 20, Issue 8, pp. 2062-8, (2001) (PubMed).

  • Target
    THO Complex 4 (THOC4)
    Alternative Name
    ALY (THOC4 Products)
    Synonyms
    THOC4 antibody, Aly antibody, ALY antibody, ALY/REF antibody, BEF antibody, REF antibody, tho4 antibody, thoc4 antibody, zgc:171753 antibody, Tho4-A antibody, alyref-a antibody, thoc4-a antibody, REF1 antibody, Refbp1 antibody, Thoc4 antibody, Tho4 antibody, Aly/REF export factor antibody, THO complex 4 antibody, Aly/REF export factor L homeolog antibody, ALYREF antibody, Thoc4 antibody, alyref antibody, alyref.L antibody, Alyref antibody
    Background
    Synonyms:
    Ally of AML1 and LEF1 antibody,BEF antibody,bZIP enhancing factor antibody,REF antibody,THO complex 4antibody,THOC 4 antibody,THOC-4 antibody,THOC4 antibody,Transcriptional coactivatorantibody
    Gene ID
    10189, 21681
    OMIM
    604171
    UniProt
    O08583
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