MAD2L1 antibody

Catalog No. ABIN108555

Product Details anti-MAD2L1 Antibody

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAD2L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Western blot with a variety of human cell lines (eg HeLa) confirms that the antibody is specific for Mad2L1.

Purification: Protein G

Immunogen: Recombinant human Mad2L1

Clone: 17D10

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try, WB: Use a concentration of 2 μg/mL. Detects a band of approximately 25 kDa (predicted molecular weight: 24.6 kDa). IP: Use a concentration of 5 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-MAD2L1 antibody (ABIN108555)

Gysin, Paquette, McMahon: "Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity." in: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1607-19, (2012) (PubMed).

Sarfraz, Hamid, Ali, Jafri, Siddiqui: "Modulations of cell cycle checkpoints during HCV associated disease." in: BMC infectious diseases, Vol. 9, pp. 125, (2009) (PubMed).

Burum-Auensen, Deangelis, Schjølberg, Røislien, Andersen, Clausen: "Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis." in: Journal of clinical pathology, Vol. 60, Issue 12, pp. 1403-8, (2007) (PubMed).

Wise, Holmes, Xie, Thompson, Wise: "Chronic exposure to particulate chromate induces spindle assembly checkpoint bypass in human lung cells." in: Chemical research in toxicology, Vol. 19, Issue 11, pp. 1492-8, (2006) (PubMed).

Target Details for MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Alternative Name: Mad2L1 (MAD2L1 Products)

Background: Synonyms:
Homolog of MAD2 S cerevisiae antibody,HsMAD 2 antibody,HsMAD2 antibody,Human mitotic feedback controlprotein Madp2 antibody,MAD 2 antibody,MAD 2A antibody,MAD2 antibody,MAD2 like 1 antibody,MAD2 like protein1 antibody,MAD2 mitotic arrest deficient like 1 antibody,MAD2A antibody,Mitotic arrest deficient like 1antibody,Mitotic arrest deficient yeast homolog antibody,Mitotic arrest deficient yeast homolog like 1antibody,Mitotic spindle assembly checkpoint protein antibody

Gene ID: 238799

OMIM: 601467

UniProt: P22626