Cytokeratin 13 antibody

Catalog No. ABIN108618

Cited in 9+ publications. The Mouse Monoclonal anti-Cytokeratin 13 antibody (Clone AE8) (ABIN108618) specifically detects Cytokeratin 13 in WB, IF, IHC (p), ICC and IHC (fro). The antibody is reactive with Human, Mouse and Rabbit samples.

Quick Overview for Cytokeratin 13 antibody (ABIN108618)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivity: Human, Mouse, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: AE8

Product Details anti-Cytokeratin 13 Antibody

Purification: Protein G purified

Immunogen: Rabbit esophageal keratins

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as guideline try at WB: 1/1000 - 1/3000. Predicted molecular weight: 50 kDa

Comment:

Myeloma, fusion partners: P3 x 63 Ag8 myeloma cells,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: Purified antibody containing PBS 0.1 % sodium azide,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-Cytokeratin 13 antibody (ABIN108618)

Zhou, Long, Hsu, Liu, Chen, Slavin, Lin, Li, Tang, Yiu, Tuffaha, Mao: "Nanofiber-Reinforced Decellularized Amniotic Membrane Improves Limbal Stem Cell Transplantation in a Rabbit Model of Corneal Epithelial Defect." in: Acta biomaterialia, (2019) (PubMed).

Parikh, Shuck, Nguyen, Herron, Donehower: "Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses." in: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 845-55, (2012) (PubMed).

Alameda, Moreno-Maldonado, Navarro, Bravo, Ramírez, Page, Jorcano, Fernández-Aceñero, Casanova: "An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells." in: Oncogene, Vol. 29, Issue 50, pp. 6522-32, (2010) (PubMed).

Leedham, Preston, McDonald, Elia, Bhandari, Poller, Harrison, Novelli, Jankowski, Wright: "Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus." in: Gut, Vol. 57, Issue 8, pp. 1041-8, (2008) (PubMed).

Moreno-Maldonado, Ramírez, Navarro, Fernández-Aceñero, Villanueva, Page, Jorcano, Bravo, Llanos Casanova: "IKKalpha enhances human keratinocyte differentiation and determines the histological variant of epidermal squamous cell carcinomas." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 13, pp. 2021-9, (2008) (PubMed).

Parikh, Nagarajan, Sei-ichi, Sinha, Garrett-Sinha: "Isolation and characterization of an immortalized oral keratinocyte cell line of mouse origin." in: Archives of oral biology, Vol. 53, Issue 11, pp. 1091-100, (2008) (PubMed).

Wada-Hiraike, Hiraike, Okinaga, Imamov, Barros, Morani, Omoto, Warner, Gustafsson: "Role of estrogen receptor beta in uterine stroma and epithelium: Insights from estrogen receptor beta-/- mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 48, pp. 18350-5, (2006) (PubMed).

Kimball, Nittayananta, Klausner, Chung, Dale: "Antimicrobial barrier of an in vitro oral epithelial model." in: Archives of oral biology, Vol. 51, Issue 9, pp. 775-83, (2006) (PubMed).

Dhouailly, Xu, Manabe, Schermer, Sun et al.: "Expression of hair-related keratins in a soft epithelium: subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of ..." in: Experimental cell research, Vol. 181, Issue 1, pp. 141-58, (1989) (PubMed).

Target Details for Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: Cytokeratin 13

Background: Synonyms:
type I cytoskeletal 13 antibody,47 kDa cytokeratin antibody,CK 13 antibody,CK-13antibody,CK13 antibody,Cytokeratin 13 antibody,Cytokeratin-13 antibody,Cytokeratin13 antibody,K13antibody,K1C13_HUMAN antibody,Ka13 antibody,Keratin 13 antibody,Keratin antibody,keratin type Icytoskeletal 13 antibody,Keratin-13 antibody,Keratin13 antibody,KRT 13 antibody,Krt-1.13 antibody,Krt1-13antibody,KRT13 antibody,MGC161462 antibody,MGC3781 antibody,Type I keratin Ka13 antibody

Gene ID: 3860, 16663

OMIM: 148065

UniProt: P13646, P08730