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IGF2 antibody (Insulin-Like Growth Factor 2) AA 25-180 Primary Antibody

IGF2 Reactivity: Human ICC, FACS, IHC, ELISA, WB Host: Mouse Monoclonal 8H1 unconjugated
Pubmed (2 references)
Catalog No. ABIN1098108
$468.60
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0.1 mg
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  • Target See all IGF2 Antibodies
    IGF2
    Binding Specificity
    • 16
    • 14
    • 13
    • 9
    • 8
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    AA 25-180
    Reactivity
    • 81
    • 28
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 80
    • 12
    • 7
    • 1
    • 1
    Mouse
    Clonality
    • 80
    • 20
    Monoclonal
    Conjugate
    • 45
    • 15
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF2 antibody is un-conjugated
    Application
    • 71
    • 40
    • 38
    • 31
    • 14
    • 13
    • 9
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    Purified recombinant fragment of human IGF2 (AA 25-180) expressed in E. Coli.
    Clone
    8H1
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.05 % sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • El Tayebi, Salah, El Sayed, Salam, Zekri, Zayed, Salem, Esmat, Abdelaziz: "Expression of insulin-like growth factor-II, matrix metalloproteinases, and their tissue inhibitors as predictive markers in the peripheral blood of HCC patients." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 16, Issue 4, pp. 346-54, (2011) (PubMed).

    Shetty, Movva, Pasupuleti, Vedicherlla, Vattam, Venkatasubramanian, Ahuja, Hasan: "Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 2, pp. 339-45, (2011) (PubMed).

  • Target
    IGF2
    Alternative Name
    IGF2 (IGF2 Products)
    Synonyms
    C11orf43, IGF-II, PP9974, LOC100136550, igf2, igf2b, wu:fc26e03, zgc:91781, igf-2, insigf, pp9974, AL033362, Igf-2, Igf-II, M6pr, Mpr, Peg2, IGFII, RNIGF2, IGF-II-B, igf2-a, igf2-b, insulin like growth factor 2, insulin-like growth factor II, insulin-like growth factor 2a, insulin like growth factor 2 S homeolog, insulin-like growth factor 2, insulin-like growth factor 2 (somatomedin A), insulin like growth factor 2 L homeolog, IGF2, LOC100136550, igf2a, igf2.S, Igf2, igf2.L
    Background
    This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    20.1 kDa
    Gene ID
    HGNC
    3481
    Pathways
    Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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