Complement Factor B antibody

Catalog No. ABIN1101457

This Goat Polyclonal antibody specifically detects Complement Factor B in IHC (p) and ID. It exhibits reactivity toward Human.

Quick Overview for Complement Factor B antibody (ABIN1101457)

Target: Complement Factor B (CFB)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Complement Factor B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunodiffusion (ID)

Product Details anti-Complement Factor B Antibody

Brand: IHC-plus™

Specificity: Human CFB / Factor B. In immunoelectrophoresis against human EDTA plasma a single precipitin line is obtained in the beta-2 region. The antiserum does not react with any other protein component of human serum or plasma. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel- diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in double radial immunodiffusion a weak reaction with mouse has been observed.

Purification: Immunoaffinity absorbed

Immunogen: Human Factor B

Type of Immunogen: Purified protein

Application Details

Application Notes: Approved: ID, IHC-P (1:200)

Usage: This product is intended for use in precipitating techniques for the identification and quantitative determination of properdin factor B in body fluids. The presence of non-precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in more sensitive techniques if proper controls are included.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water 1 ml

Concentration: Lot specific

Buffer: Lyophilized antiserum

Handling Advice: Avoid freeze/thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze/thaw cycles. Store undiluted.

Target Details for Complement Factor B

Target: Complement Factor B (CFB)

Alternative Name: CFB / Complement Factor B

Background: Name/Gene ID: CFB
Subfamily: Serine S1
Family: Protease

Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B

Gene ID: 629

UniProt: P00751

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process