Complement Factor B antibody (AA 469-494)

Catalog No. ABIN652979

The Rabbit Polyclonal anti-Complement Factor B antibody is suitable to detect Complement Factor B in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for Complement Factor B antibody (AA 469-494) (ABIN652979)

Target: Complement Factor B (CFB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21500

Product Details anti-Complement Factor B Antibody

Binding Specificity: AA 469-494

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-494 amino acids from the Central region of human CFB.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Complement Factor B

Target: Complement Factor B (CFB)

Alternative Name: CFB

Background: CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Molecular Weight: 85533

Gene ID: 629

NCBI Accession: NP_001701

UniProt: P00751

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process