Integrin beta 3 antibody

Catalog No. ABIN1102586

The Mouse Monoclonal anti-Integrin beta 3 antibody has been validated for WB, IHC, FACS, IHC (fro), IP and IHC (p). It is suitable to detect Integrin beta 3 in samples from Human, Cow, Pig, Dog and Horse.

Quick Overview for Integrin beta 3 antibody (ABIN1102586)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human, Cow, Pig, Dog, Horse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: JM2E5

Product Details anti-Integrin beta 3 Antibody

Specificity: Recognizes porcine CD61 at ~85kD expressed by platelets and megakaryocytes, but not by other hematopoietic cells. Species cross-reactivity: canine, human, bovine, equine.

Purification: Protein G purified

Immunogen: Porcine peripheral blood mononuclear cells.

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IHC-P, IP, WB (1:50 - 1:100)

Usage: Suitable for use in Flow Cytometry, Immunohistochemistry (frozen and paraffin), Immunoprecipitation, and Western Blot. Flow Cytometry: 1:50-1:100, 10 μL labels 10^6 cells in 100 μL. Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Comment:

Target Species of Antibody: Pig

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3 / Integrin Beta 3 / CD61

Background: Name/Gene ID: ITGB3
Family: Integrin

Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3

Gene ID: 3690

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex