CHRNA1 antibody (N-Term, Subunit alpha)

Catalog No. ABIN1105213

This Rabbit Polyclonal antibody specifically detects CHRNA1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHRNA1 antibody (N-Term, Subunit alpha) (ABIN1105213)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CHRNA1 Antibody

Binding Specificity: N-Term, Subunit alpha

Specificity: Recognizes CHRNA1

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse and Rat.

Purification: Immunoaffinity Chromatography

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of Human CHRNA1, identical to the related Rat and Mouse sequence

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.

Concentration: 0.5 mg/mL

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: Acetylcholine Receptor alpha Subunit

Background: CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. (1) The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule. (2)Synonyms: ACHRA, CHNRA, CHRNA1

Gene ID: 1134

NCBI Accession: NP_001034612

UniProt: P02708

Pathways: Skeletal Muscle Fiber Development