ACTN1 antibody

Catalog No. ABIN1105321

This Mouse Monoclonal antibody specifically detects ACTN1 in WB, EIA and IHC (fro). It exhibits reactivity toward Human and Chicken.

Quick Overview for ACTN1 antibody (ABIN1105321)

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Reactivity: Human, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACTN1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CB11

Product Details anti-ACTN1 Antibody

Specificity: The antibody clone CB11 is specific to the 100 kDa Alpha-Actinin polypeptide and reacts with Human and Chicken cells.

Cross-Reactivity (Details): Species reactivity (tested):Human, Chicken.

Purification: Ig Fraction

Immunogen: Purified a-actinin from Chicken gizzard. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ACTN1

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Alternative Name: alpha-Actinin-1 / ACTN1

Background: Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.Synonyms: Alpha actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin 1

Gene ID: 87

NCBI Accession: NP_001093

UniProt: P12814

Pathways: Cell-Cell Junction Organization