CCL5 antibody

Catalog No. ABIN110550

Product Details anti-CCL5 Antibody

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL5 antibody is un-conjugated

Application: Western Blotting (WB)

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

References for anti-CCL5 antibody (ABIN110550)

Adamus, Manczak, Machnicki: "Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE." in: Investigative ophthalmology & visual science, Vol. 42, Issue 12, pp. 2894-903, (2001) (PubMed).

Target Details for CCL5

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Alternative Name: RANTES (Regulated Upon Activation Normal T-Cell Expressed And Secreted) (CCL5 Products)

Synonyms: Rantes antibody, Scya5 antibody, D17S136E antibody, RANTES antibody, SCYA5 antibody, SIS-delta antibody, SISd antibody, TCP228 antibody, eoCP antibody, MuRantes antibody, C-C motif chemokine 5-like antibody, C-C motif chemokine ligand 5 antibody, chemokine (C-C motif) ligand 5 antibody, LOC100230935 antibody, CCL5 antibody, Ccl5 antibody

Background: RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T cell-specific sequences-enriched cDNA libraries1 ,2,3. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T cells and eosinophils, as well as an activator of basophils for histamine release4. In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases2.

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration