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TYROBP antibody

TYROBP Reactivity: Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN110575
  • Target See all TYROBP Antibodies
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Reactivity
    • 49
    • 20
    • 3
    Rat
    Host
    • 65
    • 1
    • 1
    Rabbit
    Clonality
    • 58
    • 9
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TYROBP antibody is un-conjugated
    Application
    • 40
    • 30
    • 26
    • 26
    • 21
    • 18
    • 12
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Top Product
    Discover our top product TYROBP Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Storage
    4 °C
  • Target
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Alternative Name
    DAP12 (TYROBP Products)
    Synonyms
    TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
    Background
    : DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is a disulfide-bonded homodimer. Crosslinking of DAP12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.
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