RGS3 antibody

Catalog No. ABIN110587

This Rabbit Polyclonal antibody specifically detects RGS3 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for RGS3 antibody (ABIN110587)

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RGS3 Antibody

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

Target Details for RGS3

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Alternative Name: RGS3 (Regulator of G Protein Signaling-3)

Background: RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed. The protein contains an RGS domain near the carboxy terminus that serve as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Gia and Gaq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling