CX3CR1 antibody

Catalog No. ABIN110594

There are 2+ publications for this product available. The Rabbit Polyclonal anti-CX3CR1 antibody is suitable to detect CX3CR1 in samples from Human. It has been validated for WB, FACS and IHC.

Quick Overview for CX3CR1 antibody (ABIN110594)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Product Details anti-CX3CR1 Antibody

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

References for anti-CX3CR1 antibody (ABIN110594)

Szukiewicz, Kochanowski, Mittal, Pyzlak, Szewczyk, Cendrowski: "CX3CL1 (fractalkine) and TNFα production by perfused human placental lobules under normoxic and hypoxic conditions in vitro: the importance of CX3CR1 signaling." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 63, Issue 3, pp. 179-89, (2014) (PubMed).

Held-Feindt, Hattermann, Mueerkoester, Wedderkopp, Knerlich-Lukoschus, Ungefroren, Mehdorn, Mentlein: "CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)." in: Experimental cell research, (2010) (PubMed).

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1 (V28, Fractalkine Receptor)

Background: Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine1. Human CX3CR1, also named V28, was first cloned from human genomic DNA libraries2. A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor3 ,4. Human CX3CR1 has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.

Pathways: Cellular Response to Molecule of Bacterial Origin