CD2 antibody (Biotin)

Catalog No. ABIN1106020

This Mouse Monoclonal antibody specifically detects CD2 in FACS and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CD2 antibody (Biotin) (ABIN1106020)

Target: CD2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: B-E2

Product Details anti-CD2 Antibody (Biotin)

Specificity: Recognizes the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography.

Immunogen: Human thymocytes. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with 1.0 mL deionised water.

Buffer: PBS containing 5 % BSA as stabilizer and 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody at 2-8 °C after reconstitution.

Target Details for CD2

Target: CD2

Alternative Name: CD2

Background: CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

Gene ID: 914

NCBI Accession: NP_001758

UniProt: P06729