CD59 antibody (FITC)
Quick Overview for CD59 antibody (FITC) (ABIN1106481)
Target
See all CD59 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Clone NaM172-2B5 recognizes the human CD59 antigen. Other species not tested.
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Purification
- Affinity chromatography
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- CD59
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Alternative Name
- CD59
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Background
- CD59 can be found in body fluids including blood plasma, saliva, amniotic fluid, seminal fluid, and urine. It is expressed as a 18-25 kD glycoprotein (in lymphocytes)anchored in the membrane by GPI tail. Since CD59 is well known membrane-associated complement regulator protein, like CD55, and present on all blood cells, anti-CD55 and anti-CD59 appear to be the most effective Mabs to detect very minor negative cell subsets (less than 1 % on erythrocytes or less than 5 % on PMN leukocytes.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
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Gene ID
- 966
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NCBI Accession
- NP_000602
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UniProt
- P13987
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Pathways
- Complement System
Target
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