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C5AR1 antibody

C5AR1 Reactivity: Human FACS, IHC (p), IHC (fro) Host: Mouse Monoclonal W17-1 unconjugated
Catalog No. ABIN1106597
  • Target See all C5AR1 Antibodies
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    Reactivity
    • 97
    • 24
    • 14
    • 12
    • 12
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 68
    • 27
    • 21
    • 1
    • 1
    Mouse
    Clonality
    • 68
    • 45
    • 2
    Monoclonal
    Conjugate
    • 64
    • 10
    • 9
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C5AR1 antibody is un-conjugated
    Application
    • 68
    • 60
    • 35
    • 19
    • 15
    • 14
    • 13
    • 13
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody detects C5aR.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Protein G
    Clone
    W17-1
    Isotype
    IgG1
    Top Product
    Discover our top product C5AR1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
    Expiry Date
    6 months
  • Target
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    Alternative Name
    CD88 / C5R1 (C5AR1 Products)
    Background
    The human anaphylatoxin C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
    Gene ID
    728
    NCBI Accession
    NP_001727
    UniProt
    P21730
    Pathways
    Complement System
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