CDK6 antibody

Catalog No. ABIN1106651

The Mouse Monoclonal anti-CDK6 antibody has been validated for WB and IF. It is suitable to detect CDK6 in samples from Human, Mouse and Rat.

Quick Overview for CDK6 antibody (ABIN1106651)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: IML-6

Product Details anti-CDK6 Antibody

Specificity: This antibody reacts to CDK6.

Purification: Affinity chromatography

Immunogen: Recombinant human Cdk6 protein.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Alternative Name: CDK6

Background: The cyclin-dependent protein kinases (CDKs) regulate major cell cycle transitions in eukaryotic cells.Cyclin-dependent kinase-6 (CDK6) is the earliest inducible member of the CDK family in human T lymphocytes, involved in growth factor stimulation and cell cycle progression. germline mutations in CDK6 do not make a significant contribution to melanoma predisposition. CDK6 gene is mapped at 7q21-q22.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE

Gene ID: 1021

NCBI Accession: NP_001250

UniProt: Q00534

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases