hCG antibody

Catalog No. ABIN1106693

The Mouse Monoclonal anti-hCG antibody is suitable to detect hCG in samples from Human. It has been validated for IHC (p).

Quick Overview for hCG antibody (ABIN1106693)

Target: hCG (Chorionic Gonadotropin (hCG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This hCG antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HCG-8

Product Details anti-hCG Antibody

Specificity: Recognizes Human Chorionic gonadotropin (beta-subunit) and does not cross reacts with other Proteins (hLH, hTSH, or hFSH).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: Purified Human Chorionic Gonadotropin.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % Sodium Acetate or neutral PBS.

Concentration: 0.1 mg/mL (after reconstitution with 1 ml PBS)

Buffer: 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for hCG

Target: hCG (Chorionic Gonadotropin (hCG))

Target Type: Hormone

Background: HCG beta (beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB).It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, β-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. HCG beta is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. Beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.Synonyms: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta

Gene ID: 1082

NCBI Accession: NP_000728

UniProt: P01233