Collagen Type V antibody

Catalog No. ABIN1106760

The Mouse Monoclonal anti-Collagen Type V antibody (Clone 13F6) (ABIN1106760) specifically detects Collagen Type V in WB, IHC (fro), IP and EIA. The antibody is reactive with Human samples.

Quick Overview for Collagen Type V antibody (ABIN1106760)

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Collagen Type V antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: 13F6

Product Details anti-Collagen Type V Antibody

Specificity: Reacts with Human pro alpha 1(V) chain.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water

Concentration: 1 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 2 % Sucrose, None

Target Details for Collagen Type V

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Alternative Name: Collagen Type V

Background: Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure.Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1

Gene ID: 1289