Glypican 3 antibody

Catalog No. ABIN1107403

This Mouse Monoclonal antibody specifically detects Glypican 3 in IF, WB, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Glypican 3 antibody (ABIN1107403)

Target: Glypican 3 (GPC3)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glypican 3 antibody is un-conjugated

Application: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 9C2

Product Details anti-Glypican 3 Antibody

Specificity: Recognizes Glypican-3 / GPC3.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.5 % protein

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Glypican 3

Target: Glypican 3 (GPC3)

Alternative Name: Glypican-3 / GPC3

Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5

Molecular Weight: 65.5 kDa

Gene ID: 2719

Pathways: Glycosaminoglycan Metabolic Process