LRP5 antibody

Catalog No. ABIN1108063

Product Details anti-LRP5 Antibody

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRP5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: Recognizes LRP5

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Clone: 2B11

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for LRP5

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Alternative Name: LRP5 (LRP5 Products)

Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.Synonyms: LRP-5, LRP7, Low-density lipoprotein receptor-related protein 5

Molecular Weight: 179 kDa

Gene ID: 4041

Pathways: WNT Signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation