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MAMLD1 antibody (N-Term)

MAMLD1 Reactivity: Human, Dog, Mouse, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1108113
  • Target See all MAMLD1 Antibodies
    MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Dog, Mouse, Xenopus laevis
    Host
    • 6
    • 2
    Rabbit
    Clonality
    • 7
    • 1
    Polyclonal
    Conjugate
    • 8
    This MAMLD1 antibody is un-conjugated
    Application
    • 8
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    LEELTKIQDP SPNELDLEKI LGTKPEEPLV LDHPQATLST TPKPSVQMSH
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, African clawed frog, DogSpecies reactivity (tested):Human
    Purification
    Purified using Protein A affinity column
    Immunogen
    The immunogen for anti-CXORF6 antibody: synthetic peptide directed towards the N terminal of human CXORF6
    Top Product
    Discover our top product MAMLD1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Add 100 μL of distilled water to a final concentration of 1 mg/mL.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • Target
    MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))
    Alternative Name
    MAMLD1 (MAMLD1 Products)
    Synonyms
    CG1 antibody, CXorf6 antibody, F18 antibody, HYSP2 antibody, G630014P10Rik antibody, mastermind like domain containing 1 antibody, mastermind-like domain containing 1 antibody, MAMLD1 antibody, Mamld1 antibody
    Background
    Mastermind-like domain-containing protein 1 or CXorf6 transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ. MAMLD1 is expressed in fetal brain, fetal ovary, fetal testis, adult brain, ovary, skin, testis, uterus and highly expressed in skeletal muscle. Defects in MAMLD1 are a cause of X-linked hypospadias type 2 (HYSP2). Hypospadias is a common malformation in which the urethra opens on the ventral side of the penis. It is considered a complex disorder with both genetic and environmental factors involved in the pathogenesis. Hypospadias can occur alone on an apparently multifactorial basis or as part of syndromes.Mastermind-like domain-containing protein 1Synonyms: CXorf6, F18, Mastermind-like domain-containing protein 1, Protein CG1
    Gene ID
    10046
    NCBI Accession
    NP_005482
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