Mammaglobin A antibody

Catalog No. ABIN1108942

This Mouse Monoclonal antibody specifically detects Mammaglobin A in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Mammaglobin A antibody (ABIN1108942)

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Reactivity: Human

Host: Mouse, Rabbit

Clonality: Monoclonal

Conjugate: This Mammaglobin A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 304-1A5-31-A5

Product Details anti-Mammaglobin A Antibody

Specificity: This Mouse/Rabbit Monoclonal (304-1A5 & 31A5) cocktail antibody Recognizes Mammaglobin (10 kDa). When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84 % has been achieved. Anti-Mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma.
Cellular Localization: Cytoplasmic.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: protein A chromatograpy.

Isotype: Cocktail

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 0.9 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Mammaglobin A

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Background: Mammaglobin, a member of the uteroglobin family, is a 10 kDa glycoprotein. Mammaglobin mRNA expression is breast tissue specific. It is overexpressed in human breast cancer. The use of Mammaglobin RT-PCR has been demonstrated to detect disseminated breast cancer. In a study to evaluate the frequency and specificity of mammaglobin, 80 % of all primary and metastatic breast tumors tested were immunopositive irrespective of tumor grade, while mammaglobin mRNA was detected in 60 % of the peripheral stem cell collections from breast cancer patients.Synonyms: MGB1, Mammaglobin-1, Mammaglobin-A, Prostatein peptide C3, Prostatic steroid-binding protein C3, Secretoglobin family 2A member 2, UGB2

Gene ID: 4250