TNC antibody

Catalog No. ABIN1109218

This Mouse Monoclonal antibody specifically detects TNC in WB, IP, IHC (p), IF and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for TNC antibody (ABIN1109218)

Target: TNC (Tenascin C (TNC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: T20

Product Details anti-TNC Antibody

Specificity: This antibody reacts to Tenascin. No cross reactivity with other proteins.

Purification: Goat anti-Mouse IgG Affinity Chromatography

Immunogen: Human Tenascin

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % Sdium Acetate or neutral PBS

Concentration: 0.1 mg/mL (after reconstitution with 1ml PBS)

Buffer: 1.2 % Sodium Acetate with 2 mg BSA as stabilizer and 0.01 mg Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for 3 months or (in aliquots) at -20 °C for longer.

Target Details for TNC

Target: TNC (Tenascin C (TNC))

Alternative Name: Tenascin / TNC / HXB

Background: The tenascins are a family of extracellular matrix proteins (ECMs). Tenascin is an extracellular matrix protein. It expressed in an unusually restricted pattern during embryogenesis and has been implicated in a variety of morphogenetic phenomena. Human hexabrachion gene(tenascin) is mapped to chromosome 9, bands q32-q34. The coding region of the hexabrachion gene spans approximately 80 kilobases of DNA and consists of 27 exons separated by 26 introns.Synonyms: Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, Myotendinous antigen, Neuronectin, TN-C, Tenascin-C

Gene ID: 3371

NCBI Accession: NP_002151

UniProt: P24821

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development