TGM3 antibody
Quick Overview for TGM3 antibody (ABIN1109311)
Target
See all TGM3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with Human TGase-3 from Human epidermal cells and recombinant Tgase-3 (rh-TG-3). This antibody recognize both full length (77 kDa) and proteolysed forms (30 kDa).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity Chromatography on Protein A
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore in distilled water.
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Buffer
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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- TGM3 (Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3))
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Alternative Name
- Transglutaminase-3 (TGM3)
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Background
- Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.Synonyms: Protein-glutamine gamma-glutamyltransferase E, TGE, TGase
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Molecular Weight
- 77 kDa
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Gene ID
- 7053
Target
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