TRIM32 antibody (C-Term)

Catalog No. ABIN1109335

This Rabbit Polyclonal antibody specifically detects TRIM32 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow and Zebrafish (Danio rerio).

Quick Overview for TRIM32 antibody (C-Term) (ABIN1109335)

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM32 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM32 Antibody

Binding Specificity: C-Term

Sequence: GFSIGSVGPD GQLGRQISHF FSENEDFRCI AGMCVDARGD LIVADSSRKE

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, ZebrafishSpecies reactivity (tested):Human

Purification: Purified on peptide immunoaffinity column

Immunogen: The immunogen for anti-TRIM32 antibody: synthetic peptide directed towards the C terminal of human TRIM32.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Expiry Date: 12 months

Target Details for TRIM32

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Alternative Name: TRIM32 / HT2A

Background: TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.Synonyms: 72 kDa Tat-interacting protein, Tripartite motif-containing protein 32, Zinc finger protein HT2A

Gene ID: 22954

NCBI Accession: NP_036342

Pathways: Negative Regulation of intrinsic apoptotic Signaling