TRIM32 antibody (AA 1-280)

Catalog No. ABIN7151256

Product Details anti-TRIM32 Antibody

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM32 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase TRIM32 protein (1-280AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRIM32

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Alternative Name: TRIM32 (TRIM32 Products)

Synonyms: BBS11 antibody, HT2A antibody, LGMD2H antibody, TATIP antibody, 1810045E12Rik antibody, 3f3 antibody, Zfp117 antibody, tripartite motif containing 32 antibody, tripartite motif-containing 32 antibody, TRIM32 antibody, trim32 antibody, Trim32 antibody

Background:

Background: Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.

Aliases: 72 kda Tat interacting Protein antibody, 72 kDa Tat-interacting protein antibody, BBS11 antibody, E3 ubiquitin-protein ligase TRIM32 antibody, HT2A antibody, LGMD2H antibody, Limb girdle muscular dystrophy 2H (autosomal recessive) antibody, Limb girdle muscular dystrophy 2H antibody, Muscular dystrophy Hutterite type antibody, TAT interactive protein 72KD antibody, TATIP antibody, TRI32_HUMAN antibody, Trim32 antibody, Tripartite Motif Containing Protein 32 antibody, Tripartite motif-containing protein 32 antibody, Zinc finger protein HT2A antibody

UniProt: Q13049

Pathways: Negative Regulation of intrinsic apoptotic Signaling