TWIST1 antibody

Catalog No. ABIN1109414

The Mouse Monoclonal anti-TWIST1 antibody has been validated for WB, EIA and IHC (fro). It is suitable to detect TWIST1 in samples from Human.

Quick Overview for TWIST1 antibody (ABIN1109414)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TWIST1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3-00E-010

Product Details anti-TWIST1 Antibody

Specificity: Reacts with Human 21 kDa TWIST1 protein. Cross reacts with Mouse, Rat and other species. It does not cross reacts with Twist-2.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Protein A Chromatography

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.1 mL distilled water to receive a concentration of 1 mg/mL.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Target Details for TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Alternative Name: TWIST1

Background: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.Synonyms: BHLHA38, Class A basic helix-loop-helix protein 38, TWIST, Twist-related protein 1

Gene ID: 7291

Pathways: p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity