TWIST1 antibody (N-Term)

Catalog No. ABIN1109415

This anti-TWIST1 antibody is a Rabbit Polyclonal antibody detecting TWIST1 in WB, EIA and IHC (fro). Suitable for Human.

Quick Overview for TWIST1 antibody (N-Term) (ABIN1109415)

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWIST1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TWIST1 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts with Human 21 kDa TWIST1 protein. It Does not cross reacts with Twist-2.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from N-terminal domain of Human Twist-1 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer

Target Details for TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Alternative Name: TWIST1

Background: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.Synonyms: BHLHA38, Class A basic helix-loop-helix protein 38, TWIST, Twist-related protein 1

Gene ID: 7291

NCBI Accession: NP_000465

Pathways: p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity