SPTAN1 antibody

Catalog No. ABIN110976

The Mouse Monoclonal anti-SPTAN1 antibody (Clone 7A3 (AA6)) (ABIN110976) specifically detects SPTAN1 in WB, IP, IF and ChIP. The antibody is reactive with Human, Mouse, Rat, Chicken, Pig, Rabbit, Guinea Pig and Mammalian samples.

Quick Overview for SPTAN1 antibody (ABIN110976)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivity: Human, Mouse, Rat, Chicken, Pig, Rabbit, Guinea Pig, Mammalian

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPTAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Clone: 7A3 (AA6)

Product Details anti-SPTAN1 Antibody

Specificity: This antibody is specific for alpha- spectrin/alpha-fodrin of all mammalian non-erythroid cells. Reacts with the 240 kDa full length alpha-fodrin molecule, the 150 kDa N-terminal cleaved product and the 120 kDa C-terminal product.

Purification: Affinity Chromatography on Protein A

Immunogen: Chicken blood cell membranes purified by hypotonic lysis and mechanical enucleation.

Isotype: IgG1

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Alternative Name: Spectrin alpha Chain (Brain) / SPTAN1

Background: Synonyms: Alpha-II spectrin, Fodrin alpha chain, SPTA2, Spectrin non-erythroid alpha chain

Gene ID: 374234

NCBI Accession: NP_001036003

UniProt: P07751

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization