SPTAN1 antibody

Catalog No. ABIN7234064

This Rabbit Polyclonal antibody specifically detects SPTAN1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SPTAN1 antibody (ABIN7234064)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTAN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SPTAN1 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Rat Spectrin alpha chain, non-erythrocytic 1 protein

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000 IHC 1:100-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Alternative Name: SPTAN1

Background: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation.

Molecular Weight:

Observed_MW: 280 kDa

Calculated_MW: 285,282 kDa

UniProt: P16086

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization