CD42b antibody

Catalog No. ABIN111204

The Mouse Monoclonal anti-CD42b antibody (Clone SZ2) (ABIN111204) specifically detects CD42b in FACS, IHC (fro) and Func. The antibody is reactive with Human samples.

Quick Overview for CD42b antibody (ABIN111204)

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD42b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: SZ2

Product Details anti-CD42b Antibody

Purification: Protein A chromatography.

Immunogen: Human washed platelets.

Isotype: IgG1

Application Details

Application Notes: Studies of platelet functions. Only suitable on frozen sections or cell smears. May be used in Western blot. Fluorescence Microscopy or Flow Cytometry: 2 g/5x10^6 platelets/test. Immunohistochemistry: Working dilution 1: 50 to 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1 mL distilled water.

Concentration: 0.2 mg/mL (prior to lyophilization)

Buffer: PBS containing 1 mg/mL BSA without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Expiry Date: 6 months

Target Details for CD42b

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Alternative Name: CD42b / GPIbA

Background: CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.Synonyms: GP-Ib alpha, GPIb-alpha, Glycoprotein Ibalpha, Platelet glycoprotein Ib alpha chain

Gene ID: 9606

UniProt: P07359