CD41, CD61 antibody (Biotin)
Quick Overview for CD41, CD61 antibody (Biotin) (ABIN111385)
Target
See all CD41, CD61 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- Protein G chromatography.
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Isotype
- IgG1
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anti-CD41,CD61 antibody
Reactivity: Human, Cow FACS, IP, ELISA, ICC Host: Mouse Monoclonal IVA30 unconjugated
anti-CD41,CD61 (PAC-1 epitope) antibodyReactivity: Human FACS, IP, ICC Host: Mouse Monoclonal PAC-1 unconjugated
anti-CD41,CD61 antibodyReactivity: Cow, Sheep, Cat, Dog, Goat, Horse, Rabbit FACS, IP, ELISA Host: Mouse Monoclonal CO-35E4 unconjugated
anti-CD41,CD61 (PAC-1 epitope) antibody (PE)Reactivity: Human FACS Host: Mouse Monoclonal PAC-1 PE
anti-CD41,CD61 (PAC-1 epitope) antibody (PerCP)Reactivity: Human FACS Host: Mouse Monoclonal PAC-1 PerCP
anti-CD41,CD61 antibody (PE)Reactivity: Chicken FACS Host: Mouse Monoclonal 11C3 PE
anti-CD41,CD61 (PAC-1 epitope) antibody (FITC)Reactivity: Human FACS Host: Mouse Monoclonal PAC-1 FITC
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Application Notes
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Suitable for use in Flow Cytometric applications: 1 g to stain 1.0 x 10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL (OD280 nm)
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Buffer
- 0.01 M PBS, pH 7.2, containing 2.0 mM EDTA and 1.0 % BSA as buffer and 0.09 % Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- CD41, CD61 (CD41,CD61)
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Background
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
Target
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