CD41, CD61 antibody (PAC-1 epitope) (PerCP)

Catalog No. ABIN7505934

This Mouse Monoclonal antibody specifically detects CD41, CD61 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD41, CD61 antibody (PAC-1 epitope) (PerCP) (ABIN7505934)

Target: CD41, CD61 (CD41,CD61)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD41, CD61 antibody is conjugated to PerCP

Application: Flow Cytometry (FACS)

Clone: PAC-1

Product Details anti-CD41, CD61 Antibody (PerCP)

Binding Specificity: PAC-1 epitope

Purpose: Anti-Hu CD41/CD61 (PAC-1 epitope) PerCP

Characteristics: The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

Purification: Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human platelets

Isotype: IgM, kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Alternative Name: CD41/CD61

Background: CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.,platelet GPIIb, Integrin alpha-Iib, GPalpha IIb, GPIIb, GT, GP3A, platelet GPIIIa

Gene ID: 35