Factor XI antibody

Catalog No. ABIN111407

Product Details anti-Factor XI Antibody

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Factor XI antibody is un-conjugated

Application: Western Blotting (WB), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: Reacts with human Factor XI.

Purification: Ammonium sulfate precipitation, ion exchange chromatography and gel filtration

Immunogen: Human Factor XI

Clone: HfXI-2

Isotype: IgG

Application Details

Application Notes: Inhibitory in clotting assays. Useful for purification of Factor XI. Western blot (non-reduced samples only, band size 160 kD). RIA. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 12.4 mg/mL (OD280 nm, E1% = 14)

Buffer: 50 % (vol/vol) glycerol/water) without preservatives

Preservative: Without preservative

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Target Details for Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Abstract: F11 Products

Synonyms: FXI antibody, 1600027G01Rik antibody, AI503996 antibody, Cf11 antibody, LRRGT00086 antibody, coagulation factor XI antibody, F11 antibody, CpipJ_CPIJ000593 antibody, CpipJ_CPIJ001060 antibody, CpipJ_CPIJ002752 antibody, CpipJ_CPIJ003631 antibody, CpipJ_CPIJ004041 antibody, CpipJ_CPIJ004093 antibody

Background: Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a haemorrhagic condition of variable severity.Synonyms: FX1, PTA, Plasma thromboplastin antecedent

Gene ID: 2160

NCBI Accession: NP_000119

UniProt: P03951