Neisseria Gonorrhoeae antibody

Catalog No. ABIN7101957

The Mouse Monoclonal anti-Neisseria Gonorrhoeae antibody (Clone 801) (ABIN7101957) specifically detects Neisseria Gonorrhoeae in IA. The antibody is reactive with Neisseria Gonorrhoeae samples.

Quick Overview for Neisseria Gonorrhoeae antibody (ABIN7101957)

Target: Neisseria Gonorrhoeae

Reactivity: Neisseria Gonorrhoeae

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neisseria Gonorrhoeae antibody is un-conjugated

Application: Immunoassay (IA)

Clone: 801

Product Details anti-Neisseria Gonorrhoeae Antibody

Purification: Protein G chromatography.

Immunogen: Pool of UV-inactivated N. gonorrhoeae cells. Neisseria Reference Laboratory strains G-7, R-11 and 71222 (W-I), 5766 and 8038 (W-II), 8660 (W-III).

Isotype: IgG2b

Application Details

Application Notes: Suitable for use in ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.52 mg/mL (OD280 nm)

Buffer: PBS buffer, pH 7.4, without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Neisseria Gonorrhoeae

Target: Neisseria Gonorrhoeae

Target Type: Bacteria

Background: Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).