IBA1
Reactivity: Human
WB, IHC
Host: Rabbit
Monoclonal
unconjugated
Application Notes
Immunohistochemistry on Paraffin Sections: 5 μg/mL (1/40). Pretreatment is not necessary. Suggested Positive Control: Human spleen. This antibody does not react on routinely processed Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore by adding 0.5 mL distilled water.
Concentration
0.2 mg/mL
Buffer
PBS containing 5 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
This product is photosensitive and should be protected from light
Storage
4 °C
Storage Comment
Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE!
Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1