The Mouse Monoclonal anti-Cardiac Troponin T2 antibody has been validated for WB and EIA. It is suitable to detect Cardiac Troponin T2 in samples from Human and Cow.
This antibody is specific for Cardiac Troponin T and does not react with the Skeletal form. The epitope has been mapped to a region between amino acids 60-71 of the native protein.
No Cross-Reactivity
Fish, Rat (Rattus), Goat, Dog (Canine), Pig (Porcine), Mouse (Murine), Cat (Feline), Rabbit
cTnT
Reactivity: Human, Mouse, Rat
WB, ELISA, IHC, ICC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
Cardiac Troponin T2 (cTnT)
(Cardiac Troponin T (cTnT))
Alternative Name
Cardiac Troponin T
Background
Cardiac Troponin T, a 36 kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.Synonyms: TNNT2, TnTc, cTnT