Neisseria Gonorrhoeae antibody (HRP)
Quick Overview for Neisseria Gonorrhoeae antibody (HRP) (ABIN112793)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Molar Ratio: HRP:IgG substitution is 2-3.
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Immunogen
- Whole N. gonorrhoeae, ATCC 31426
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Application Notes
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Suitable for use in immunocytochemistry and ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1-2 mg/mL (OD280 nm, E0.1% = 1.4)
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Buffer
- PBS containing 10 mg/mL BSA as stabilizer and 0.002 % Thimerosal as preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Neisseria Gonorrhoeae
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Target Type
- Bacteria
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Background
- Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).
Target
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