HBSAg antibody (HRP)
Quick Overview for HBSAg antibody (HRP) (ABIN112970)
Target
See all HBSAg (HBsAg) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Molar Ratio: HRP: IgG substitution is 2-3
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Immunogen
- Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.
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Application Notes
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Suitable for use in ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1-2 mg/mL (OD280 nm, E0.1% = 1.4)
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Buffer
- PBS containing 10 mg/mL BSA as stabilizer and 0.002 % Thimerosal as preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))
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Alternative Name
- Hepatitis B Surface Antigen / HBsAg
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Target Type
- Viral Protein
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Background
- Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.Synonyms: HBV surface antigen, Hepatitis B Virus
Target
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